© 2016 by INFN. Even within the Constrained Minimal Supersymmetric Standard Model (CMSSM), it is possible to induce sfermion avor mixing through the Renormalization Group Equations (RGE) when the full structure of the Yukawa couplings is considered. We analyze the impact of including those effects on the accurate computation of B-physics observables, electroweak precision observables (EWPO) and the Higgs boson mass predictions.